Wwp2 ubiquitylates rna polymerase ii for dna-pk-dependent transcription arrest and repair at dna breaks

HIGHLIGHTS

• who: DNA double-strand break repair and collaborators from the Department Leiden University Medical Center, ZC Leiden, The Netherlands have published the article: WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks, in the Journal: (JOURNAL)
• what: The authors show that the ubiquitin ligase associates with components of the and complexes and is recruited to DSBs at transcribed genes. The authors provide insight into the molecular events that lead to transcription silencing induced by DSBs at RNAPII transcribed genes. The authors provide several lines of evidence supporting a . . .
  

   

  

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