Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating ampk through the purine salvage pathway

HIGHLIGHTS

  • What: This study demonstrated that XOR inhibition has a cytoprotective effect against HG-induced GEC injury by activating AMPK through the purine salvage_pathway.
  • Who: Keum-Jin Yang from the Clinical Research Institute, Daejeon StMary’s Hospital, Daejeon, Republic of Korea Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of have published the research work: Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating AMPK through the purine salvage pathway, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    XOR inhibition . . .

     

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