HIGHLIGHTS
- who: Francesco Fazio from the Rome, ItalySapienza University have published the article: Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia, in the Journal: Scientific Reports Scientific Reports
- how: All in_vivo and in_vitro experiments were carried out in accordance with the European (86/609/EEC) and Italian (DL.116/92) guidelines of animal care.
SUMMARY
In contrast, KYNA acts as a competitive antagonist at the glycine site of the GluN1 subunit of NMDA receptors, thereby inhibiting NMDA receptor function4. KMO activity is reduced in . . .
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