Xat as an automated flow platform to increase fsp3 in drug [a] [b]

HIGHLIGHTS

• who: Pijper and Brenda [JACES] from the Calle Jarama A, Toledo, Spain RWTH Aachen University have published the article: XAT as an automated flow platform to increase Fsp3 in drug [a] [b], in the Journal: (JOURNAL)
• what: The authors report the combination of continuous flow with photochemistry to create an automated platform for library synthesis using halogen atom transfer (XAT) reaction to increase Fsp3 in drug molecules. The authors show that various amino-protecting groups are accepted in the system, such as Cbz or phthalimide .
• how: The best results were obtained when iodo . . .
  

   

  

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