Xct, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases

HIGHLIGHTS

  • who: Johnan A. R. Kaleeba and Zhiqiang Qin from the Research Center forTongji University Medicine, Shanghai, China have published the paper: xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases, in the Journal: (JOURNAL)
  • what: The findings of a role for KSHV in regulation of its own receptor were the first to demonstrate a direct link between xCT receptor usage and KSHV pathogenesis, and have inspired ongoing work aimed at defining post-entry interactions of KSHV with the human host that can be explored as viable therapeutic . . .

     

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