Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats

HIGHLIGHTS

  • who: . and collaborators from the University of Huddersfield, United Kingdom have published the research: Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats, in the Journal: (JOURNAL)
  • what: This study was undertaken to investigate whether inhalation of xenon gas ameliorates neonatal sepsis-induced neurodevelopmental impairment at early adulthood age in rats via modulation of apoptotic and/or necroptotic cell death pathways. The authors demonstrated that repeated LPS administration in rat pups resulted in cognitive deficit in juvenile rats and impaired synapse integrity, reflected as significantly decreased expression of key . . .

     

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