Xmu-mp-1 attenuates osteoarthritis via inhibiting cartilage degradation and chondrocyte apoptosis

HIGHLIGHTS

  • who: XMU-MP- and collaborators from the University, China have published the Article: XMU-MP-1 attenuates osteoarthritis via inhibiting cartilage degradation and chondrocyte apoptosis, in the Journal: (JOURNAL)
  • what: The authors identified XMU-MP-1 as a compound with effects of anti-cartilage degeneration using in_vitro and in_vivo OA models. Based on the results , the authors propose that restoring YAP in OA chondrocytes might have chondroprotective effects against arthritis. EdU labeling experiments were carried out to explore the function of XMU-MP-1 in chondrocyte proliferation regulation. The work demonstrated that XMU-MP1 promotes . . .

     

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