Xpc-parp complexes engage the chromatin remodeler alc1 to catalyze global genome dna damage repair

HIGHLIGHTS

• who: Charlotte Blessing from the School Leiden University of Quebec (CHUL site), Quebec City, Canada have published the Article: XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: Although several studies identified XPC as a target of PARylation in_vitro and upon exogenous DNA damage treatment of cultured cells with H2O248-50, the analysis shows that XPC is not PARylated in response to UV-C irradiation. The authors propose that the early recognition of 6-4PPs by XPC and the transient response . . .
  

   

  

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