Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo

HIGHLIGHTS

• who: Caroline S. de Freitas et al. from the Virologia Molecular, Instituto Biologia, Universidade do (UFRJ), (ICB), Universidade (UFMG), Brazil have published the article: Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo, in the Journal: (JOURNAL) of January/30,/2019
• how: The authors showed that sofosbuvir clinically approved against hepatitis C inhibits yellow fever virus replication in liver cell lines and animal models. Both male and female mice were used in the experiments. This result is consistent with the observations from immunodetection of viral dsRNA (Fig 4). Most commonly the . . .
  

   

  

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