Zebrafish cancer avatars: a translational platform for analyzing tumor heterogeneity and predicting patient outcomes

HIGHLIGHTS

  • who: Majd A. Al-Hamaly and colleagues from the Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA have published the Article: Zebrafish Cancer Avatars: A Translational Platform for Analyzing Tumor Heterogeneity and Predicting Patient Outcomes, in the Journal: (JOURNAL)
  • what: In this experiment, before engraftment, human rhabdomyosarcoma cells were made to stably express the FUCCI4 cell-cycle fluorescent reporter. Twenty-four patients with pancreatic, colon and gastric cancers undergoing chemotherapy were enrolled in the study, and their biopsies were used to generate avatar models.
  • how: In this study patients were considered . . .

     

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