HIGHLIGHTS
- who: Faiza Basheer et al. from the School of Medicine, Deakin University, Geelong, VIC, Australia have published the article: Zebrafish Models of Paediatric Brain Tumours, in the Journal: (JOURNAL)
- what: In this review, the authors focus on the key transgenesis techniques currently employed for paediatric cancer modelling in zebrafish . This model provides a strong platform for performing pre-clinical studies and drug screening that could prevent malignant transformation of the GBM subtype . This study reports HES3 transcription factor, which is important for the developing brain and inhibits neural stem_cell differentiation as a mediator for oncogenesis . . .
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