Zfp14 regulates cancer cell growth and migration by modulating p53 protein stability as part of the mdm2 e3 ubiquitin ligase complex

HIGHLIGHTS

  • who: Shakur Mohibi and collaborators from the Comparative Oncology Laboratory, Schools of Veterinary Medicine and Medicine, University of California, Davis, CA, USA have published the Article: ZFP14 Regulates Cancer Cell Growth and Migration by Modulating p53 Protein Stability as Part of the MDM2 E3 Ubiquitin Ligase Complex, in the Journal: Cancers 2022, 14, 5226. of /2022/
  • what: The biological functions of most KRAB-ZFPs are unknown and thus the identification of the physiological and cancer-specific function of ZFP14 is significant.
  • how: For this the authors used wild-type p53 containing human cancer . . .

     

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