Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells

HIGHLIGHTS

• who: Nilda Vanesa Ayala-Nunez from the CNRS Clifton Rd NE, MS:, Atlanta, GA, University have published the paper: Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show that ZIKV-infected monocyte-derived cells are found in the CNS of a human fetus with microcephaly and the authors assessed monocyte-driven ZIKV dissemination and damage in ex vivo culture models, including human embryonic stem_cell (hESC)-derived cerebral organoids and organotypic mouse cerebellar slices. The authors propose a model in which . . .
  

   

  

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