Zika virus infection in pregnancy: a protocol for the joint analysis of the prospective cohort studies of the zikalliance, zikaplan and zikaction consortia

HIGHLIGHTS

  • who: A E Ades and collaborators from the ZIKV IPD Consortium protocol differs in two other waysFirst it proposes to include surveillance studies, which may result in overestimating the risk of adverse outcomes due to retrospective ascertainment of infected women following adverse newborn outcomes., Second, congenital infection is to be defined by clinical and radiological criteria alone. Other statistical methods may have been developed by the time the data becomes available for these analyses. Whatever form of analysis is adopted, a standardised pooled analysis from three large consortia comprising , centres will provide valuable information about these parameters . . .

     

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