Znf281 promotes colon fibroblast activation in tgf1-induced gut fibrosis

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  • who: Ilaria Laudadio et al. from the Department of Molecular Medicine, Sapienza University, Rome, Italy have published the article: ZNF281 Promotes Colon Fibroblast Activation in TGF1-Induced Gut Fibrosis, in the Journal: (JOURNAL) of 25/01/2017
  • what: The aim of this study is to investigate in vivo and in vitro the role of in intestinal fibrogenesis. The authors report findings that implicate, for the first time, ZNF281 as a direct participant in intestinal fibrogenesis. Since mechanisms underlying fibrogenesis in chronic colitis are largely unknown, the authors aimed to deeper explore this issue. The authors . . .

     

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