HIGHLIGHTS
- What: The authors investigated the impact of prenatal exposure to the opioid buprenorphine on the excitatory synaptogenic signaling and morphological development of astrocytes during a key time period for these processes, with potential implications for long-term synaptic connectivity and function in the POE brain. This approach provides an accurate estimation of the synapse number based on the precise localization of pre- and postsynaptic proteins, which localize to separate compartments of neurons and only appear to overlap in fluorescencebased ICC when directly opposed at synaptic junctions .
- Who: Ethan B. Niebergall and colleagues from the Department . . .
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