HIGHLIGHTS
- What: In this study using endothelial cell-specific human Nox4 transgenic (TG) mice and endothelial cell-specific Nox4 conditional knockout (cKO) mice the authors investigated the impact of Nox4 upregulation on PECAM-1 expression in mouse retinas and brain microvascular endothelial cells (BMECs). The authors seek to understand if increased Nox4 expression in ECs contributes to BRB breakdown through regulation of PECAM-1.
- Who: Jinli Wang et al. from the Sciences, University at Buffalo, State University of New York, Buffalo, NY, United States of America have published the Article: Effects of Nox4 upregulation on PECAM . . .
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