HIGHLIGHTS
- What: To address this problem the authors investigate a target-controlled dialysis by in vitro experiments - a novel technique in which is spiked into the dialysis solution to make use of the physicochemical properties of renal replacement therapy for solute transport with the goal to reduce the risk of inadequate exposure. To address this problem, the authors propose a novel modification of traditional hemodialysis, which the authors call target-controlled dialysis (TCD), with the main objective of keeping antibiotic levels within the optimal range throughout RRT. This study shows the concept and identifies prerequisites of TCD through . . .

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