The combination of butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and th17/treg

HIGHLIGHTS

  • What: The research findings suggest that a decrease in the concentration of 3-HAA may be one of the reasons for bone loss . The aim of this study is to examine the effects of the combination of the probiotic strain Bp and 3-HAA in PMO rats. The study demonstrated that combined treatment with Bp and 3-HAA could alleviate the disruption of gut microbiota in PMO caused by estrogen deprivation. In the upcoming research, the authors plan to select several microbiotas that show significant correlations and establish a PMOrelated risk model through bioinformatics analysis, aiming to . . .

     

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