HIGHLIGHTS
- What: This study aims to evaluate the in_vitro biological effects of irisin on the BV2 microglial cellular model in culture, focusing on its potential as a neuroprotective and anti-inflammatory agent. By assessing its effects on the NLRP3 inflammasome pathway, this research seeks to demonstrate irisin`s ability to modulate various inflammatory and anti-inflammatory pathways involved in the pathogenesis and progression of neurodegenerative diseases. The authors aimed to further characterize the anti-inflammatory properties of irisin by investigating its possible influence on the NLRP3 inflammasome. The aim of this study was to demonstrate that irisin, a . . .

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