Antidepressant effects of activation of infralimbic cortex via upregulation of bdnf and β-catenin in an estradiol withdrawal model

HIGHLIGHTS

  • What: The study demonstrated that estradiol withdrawal elicited a depression- and anxiety-like state in rats and downregulated the BDNF/β-catenin expression in the IL, which could be reversed with ALLO supplementation.
  • Who: Wenhua Zhou et al. from the Department of Obstetrics, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, PRChina have published the paper: ORIGINAL INVESTIGATION, in the Journal: (JOURNAL)
  • How: The flowchart of the studies was presented in Figs 1A and 2A. All statistical data were analyzed using GraphPad Prism 7.0 software (San Diego CA USA) shown as the mean . . .

     

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