Crispr-cas9 screening develops an epigenetic and transcriptional gene signature for risk stratification and target prediction in neuroblastoma

HIGHLIGHTS

  • What: Conceptualization, Supervision, Writing-review and editing, Resources.
  • Who: SCH et al. from the Nanjing Medical, China have published the research work: CRISPR-Cas9 screening develops an epigenetic and transcriptional gene signature for risk strati fi cation and target prediction in neuroblastoma, in the Journal: (JOURNAL)
  • How: To address these challenges the authors conducted an integrative analysis using CRISPR-Cas9 knockout screening and other NB transcriptomic methods to develop an EP-TF gene signature providing a new diagnostic and prognostic tool. To further elucidate the role these 35 pivotal EP-TF genes in . . .

     

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