Effect of metabolic status on response to siv infection and antiretroviral therapy in nonhuman primates

HIGHLIGHTS

  • What: PK has served as a consultant to Alnylam Pharmaceuticals and receives research support from Novo Nordisk for studies unrelated to the work . published under the terms of the International License. The authors exploited the rhesus macaque model of SIV infection and ART to assess the effect of preexisting obesity/insulin resistance on viral dynamics and efficacy of ART suppression as well as an array of immunological and metabolic parameters. Since the primary focus of the study was on the potential effects of ART on various aspects of metabolic disease and the potential additional burden of preexisting . . .

     

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