HIGHLIGHTS
- Who: Danya Zhou from the National Institutes Health (NIH), United States Ohio University, United States have published the paper: Neutrophils in oncolytic virus immunotherapy, in the Journal: (JOURNAL)
- How: The study compared the effects of parental MV ultraviolet-irradiated MV and MV-GM-CSF. Indicated that intratumoral injection of MV could reduce or eliminate tumor progression with MV-GM-CSF further enhancing the oncolytic effect.
- Future: Future studies should focus on finding a balance between inhibiting neutrophil activity to increase OV replication in tumor cells and subsequently activating neutrophils to counteract the immunosuppressive . . .
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