HIGHLIGHTS
- What: This study aimed to both identify and address theoretical and methodological challenges to evaluating the efficacy of preventive interventions such as BaSICS in restoring typical neuroendocrine rhythms for preadolescent youth living in poverty. Next, the authors propose a theoretical model of multisystem stress response function in the context of PRS to provide conceptual clarity to classic single-system findings and hypothesize about comprehensive multisystem targets of intervention when studying PRS-exposed preadolescents. The authors discuss how contemporary multisystem, person-centered approaches may help to clarify weak and inconsistent cortisol-maladjustment links identified in studies adopting classic . . .

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