HIGHLIGHTS
- who: Chooyoung Baek et al. from the 6, IFD, Paris, France, The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of have published the paper: Mib1 prevents Notch Cis-inhibition to defer differentiation and preserve neuroepithelial integrity during neural delamination, in the Journal: (JOURNAL) of March/29,/2018
- what: The authors show that Notch signaling which is classically associated with an undifferentiated state remains active in prospective neurons until they delaminate. The authors propose that the fine-tuned balance between Notch Trans-activation and Cis-inhibition allows neuroepithelial cells to seamlessly delaminate . . .
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