HIGHLIGHTS
- who: Paola C. Rosas from the First Hospital, Peking University, China have published the research work: Implications of S-glutathionylation of sarcomere proteins in cardiac disorders, therapies, and diagnosis, in the Journal: (JOURNAL)
- what: In view of evidence discussed below that cardiac myosin binding protein C (cMyBP-C), actin, cardiac troponin I (cTnI) and titin are modified by S-glutathionylation, the authors focus here on these sarcomere proteins in physiological control of cardiac function by this oxidative related and potentially maladaptive post-translational modification.
- how: Showed that the cTnIcTnC interaction senses sarcomere length . . .
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