HIGHLIGHTS
- who: Endogenous Antigen Processing and colleagues from the Department of Functional Genomics, KRIBB School of Bioscience, University of Science and Science Center, United States have published the research: Maintenance of Hypoimmunogenic Features via Regulation of Endogenous Antigen Processing and Presentation Machinery, in the Journal: (JOURNAL)
- what: The authors showed that the hypoimmunogenic properties of gene-edited cell lines can be disrupted by epigenetic factors that arose during differentiation into functional derivatives and can be retained by overexpression of the transcription factors, RelA and NLRC5.
- future: Further work is needed to enhance the utility . . .
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