HIGHLIGHTS
SUMMARY
In_vitro grown human cell-derived tissue engineered matrices (TEMs) have been recently proposed as a promising material to fulfill the need for an easily accessible and an off-the-shelf option for TEHV development. TEMs are obtained by in_vitro culture of human fibroblastlike cells on a biodegradable scaffold for a pre-determined amount of time to have sufficient deposition of ECM proteins. It has been shown that residual cellular debris, such as DNA, mitochondria and cell membrane_proteins, can promote a pro-inflammatory M1 macrophage phenotype both in_vitro and in_vivo. Indeed, the DNA amount and . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.