HIGHLIGHTS
- who: Yukie Tanaka from the United States Monash University, Australia have published the paper: Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination, in the Journal: (JOURNAL)
- what: The authors focused on the mechanism(s) underlying RIG-I inhibition by M2-2. This study has revealed that the mechanism underlying HMPV-M2-2 protein-mediated innate immune inhibition is similar to that by V proteins of several members of the family Paramyxoviridae .
- how: These results indicated that M2-2 inhibits RIG-I/TRIM25 signaling and suppresses . . .
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