HIGHLIGHTS
- who: Elise L. Kessler and collaborators from the Department of Medical Physiology, Division of Heart and Lungs, University Medical Center Utrecht, GA Utrecht, The Netherlands have published the article: Ventricular TLR4 Levels Abrogate TLR2-Mediated Adverse Cardiac Remodeling upon Pressure Overload in Mice, in the Journal: (JOURNAL)
- what: The authors showed that ventricular TLR4 levels were high in failing murine hearts during cardiac dysfunction and, indeed, demonstrated a possible correlation of ventricular TLR2 and TLR4 during pressure overload.
- how: In the study TAC animals with TLR2 deficiency showed reduced levels of hypertrophy as . . .
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