A first look at arfome: dual-coding genes in mammalian genomes

HIGHLIGHTS

  • who: Wen-Yu Chung and collaborators from the Center forState University have published the research: A First Look at ARFome: Dual-Coding Genes in Mammalian Genomes, in the Journal: (JOURNAL)
  • what: The authors show that although dual coding is nearly impossible by chance a number of human transcripts contain overlapping coding regions. The test is based on the following reasoning: in most standard protein-coding regions (with only one reading_frame), j at the third codon position (j3) is significantly different (higher) than at the first and second codon positions (j12), so that j12, j3 .
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