A blood glucose fluctuation-responsive delivery system promotes bone regeneration and the repair function of smpd3-reprogrammed bmsc-derived exosomes

HIGHLIGHTS

  • What: The authors focused on the potential value of Smpd3 in autophagic activation and considered its use as a target to further enhance the endogenous autophagy levels of BMSCs, subsequently restoring damaged BMSC function and affecting bone regeneration in T2DM patients. The authors used stem_cell exosomes overexpressing Smpd3, which require no complex modifications compared to exosomes modified in_vitro.
  • Who: Lingxiao Wang from the (UNIVERSITY) have published the Article: A blood glucose fluctuation-responsive delivery system promotes bone regeneration and the repair function of Smpd3-reprogrammed BMSC-derived exosomes, in the Journal: (JOURNAL) of 15/Dec . . .

     

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