An extended catalog of integrated prophages in the infant and adult fecal microbiome shows high prevalence of lysogeny

SUMMARY

    Previous studies have explored the dynamics and diversity of the infant gut virome and suggested the importance of temperate_phage lifestyle in infant gut microbiome (Lim et_al, 2015; Bushman and Liang, 2021; Shah et_al, 2023; Walters et_al, 2023). MAGs enable also the characterization of prophage - bacterial host relationships (Nayfach et_al, 2021c; Johansen et_al, 2022; Tomofuji et_al, 2022). Between 30 and 75% of all complete sequenced bacterial genomes independent of the ecosystem contain one or more prophage sequence (Casjens, 2003; Roux et_al, 2015; López-Leal et_al, 2022), and they have been shown to modulate their host fitness by . . .

     

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