Causal relationship of interleukin-6 and its receptor on sarcopenia traits using mendelian randomization

HIGHLIGHTS

• What: The aim of this study was to comprehensively investigate the causal relation for IL-6 or sIL6 with sarcopenia using a two-sample Mendelian randomization approach, and to determine whether targeting these factors may be a viable approach to preventing or treating muscle loss. These findings suggest that, within the limits of the study design and the genetic instruments employed, sarcopenia traits do not exert a detectable causal influence on IL-6 or IL-6R levels. The study has several limitations that should be considered when interpreting the findings .
• Who: Interleukin and collaborators from . . .
  

   

  

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