Characterization of mirna profiling in konjac-derived exosome-like nanoparticles and elucidation of their multifaceted roles in human health

HIGHLIGHTS

• What: The aim of this study is to provide an in-depth characterization of K-ELNs and their associated miRNAs, with particular emphasis on investigating their potential human gene targets across various biological kingdoms. It is important to note that the analysis of A. albus sequencing data was conducted using the A. konjac genome as a reference, due to the current unavailability of a published A. albus genome. Subsequent to TEM analysis, NTA analysis was conducted to determine the diameter of the K-ELNs. Given the low expression levels of certain miRNAs, the authors focused on the . . .
  

   

  

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