Circulating anti-endothelial cell antibodies in patients with geographic atrophy related to dry age-related macular degeneration

HIGHLIGHTS

  • What: As inflammation and immune system involvement are strongly suggested to play a central role in promoting the degenerative process and stimulating the onset complications the authors aimed to analyze the frequency serum anti-retinal (ARAs) and anti-endothelial cell antibodies (AECAs) in patients with dry AMD and to determine their relationship with the clinical features the disease notably the area geographic atrophy (GA). This study shows a higher prevalence AECAs in patients with dry AMD; however no correlation was found between the serum levels these autoantibodies and the area GA. medicina60050810 This study is the first . . .

     

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