Decaf: a novel method to identify cell-type specific regulatory variants and their role in cancer risk

HIGHLIGHTS

• who: Cynthia A. Kalita from the Division of Population Sciences, USA have published the research work: DeCAF: a novel method to identify cell-type specific regulatory variants and their role in cancer risk, in the Journal: (JOURNAL)
• what: The authors propose DeCAF (DEconvoluted cell type Allele specific Function) a new to identify cell-fraction (cf) QTLs in tumors by leveraging both allelic and total expression information. To further improve power for testing in the xCell results, the authors focus on using cell types with a cell fraction score with an interquartile range >0.1 and . . .
  

   

  

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