HIGHLIGHTS
- What: The review examines perspectives on the physiological adaptations induced by thermal interventions, particularly in relation to epigenetic modifications. This study shows that there is a strong dose-response relationship for heat intervention, and that a difference of 1 °C during HWI can lead to different results. The results of the study show that 4 h post-exercise, the promoter of PPAR-delta exhibited hypermethylation in the overnight fasting condition only. This study demonstrated the beneficial effect of heat application using thermal blankets (40.5-41.5 °C, 30 min/day for 7 days) on the autophagic . . .
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