HIGHLIGHTS
- who: Hsiao-Fan, Chen and Kou-Juey, Wu from the Research Center for Tumor Medical Science, Graduate Institute of Cancer Biology, China Medical University, Taichung, Taiwan have published the research: Endothelial Transdifferentiation of Tumor Cells Triggered by the Twist1-Jagged1-KLF4 Axis: Relationship between Cancer Stemness and Angiogenesis, in the Journal: (JOURNAL) of 26/08/2015
- what: Tumor hypoxia is associated with malignant biological phenotype including enhanced invasiveness, angiogenesis, migration, and metastasis.
- how: The results showed that Jagged1/Notch pathway can regulate the expression of KLF4 by directly binding to the KLF4 promoter . . .
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