Enhanced angiogenic properties of umbilical cord blood primed by op9 stromal cells ameliorates neurological deficits in cerebral infarction mouse model

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  • who: Yasunori Yoshida from the DepartmentMedical University have published the article: Enhanced angiogenic properties of umbilical cord blood primed by OP9 stromal cells ameliorates neurological deficits in cerebral infarction mouse model, in the Journal: Scientific Reports Scientific Reports
  • what: The authors focused on the gene_expression features of the monocytic cluster. This study demonstrated that OP9 strongly and rapidly augmented the pro-angiogenic characteristics of UCB cells (Fig 2), partly by shifting their phenotype in the monocytic fraction toward an angiogenic M2 dominant status (Fig 3). In the models , these behavioral abnormalities due to MCAO can . . .

     

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