Flow-cytometry assessment of dna content and immunophenotyping of immune-cells in lymph-node-specimens as a potential diagnostic signature of aggressiveness in b-non-hodgkin lymphomas

HIGHLIGHTS

• What: The authors aim to focus on LN biopsies and extend the previous observations to include specimens of CD10 positive and negative B-NHLs. Analysis of the surrounding immune cells in the study demonstrated lower percentages of total C ­ D45 + cells in aggressive relative to indolent B-NHLs. The study shows potential diagnostic utility for integration of PF and iGr in differentiating specimens with aggressive and indolent B-NHLs by FC, with high specificity and sensitivity.
• Who: David Azoulay from the Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel have published the research work . . .
  

   

  

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