HIGHLIGHTS
- who: Cheng Zhou and collaborators from the Department of Hematology, Xiangya Hospital, Central South University, Changsha, China, Department of Geriatric have published the paper: Hymeglusin Enhances the Pro-Apoptotic Effects of Venetoclax in Acute Myeloid Leukemia, in the Journal: (JOURNAL)
- what: As hymeglusin decreased BCL2 expression, venetoclax could inhibit the activity of BCL2; thus, a combination strategy of both inhibitors was considered. The study showed that similar effects were achieved with a lower concentration of venetoclax combined with hymeglusin than with venetoclax alone. In primary cells, the combinatorial strategy with hymeglusin and venetoclax showed Frontiers . . .
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