HIGHLIGHTS
- What: Approval for the study was obtained from the Medical Ethics Committee of the hospital (approval no. 2020122), and informed consent was obtained from all participants.
- Who: Pengpeng Yue from the Animals SD rats (adult, male, g) were provided by Wanqian Jiaxing Biotechnology Co [, ]Ltd., Wuhan, China. The rats were housed in a pathogen-free environment at the Animal Laboratory Center, Zhongnan Hospital of Wuhan University. They were fed a methionine‒cholinedeficient (MCD) diet (10% fat content, purchased from Xietong Pharmaceutical Bioengineering Co., Ltd., Jiangsu, China.) for , weeks to establish a fatty liver model (≥60 . . .

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