In vivo evaluation of integrin αvβ6-targeting peptide in nsclc and brain metastasis

HIGHLIGHTS

• who: Di Fan and colleagues from the Jinan University, China have published the Article: In vivo evaluation of integrin u03b1vu03b26-targeting peptide in NSCLC and brain metastasis, in the Journal: (JOURNAL)
• what: The authors aimed to develop 68Ga-labeled or Cy5.5-labeled peptide G2-SFLAP3 (GGGRGDLGRL), and investigated the imaging effect of G2-SFLAP3 for both subcutaneous and brain-metastatic NSCLC in xenograft mice models. In the current research, G2-SFLAP3-Cy5.5 showed high and specific accumulation in integrin avb6-positive tumor lesions; and had potential value for intraoperative surgical guidance in patients . . .
  

   

  

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