Intrathecal chemotherapy for the management of lymphoblastic lymphoma in a 4-year-old dog: a case report

SUMMARY

    Primary or secondary central nervous system lymphoma (CNS) is clinically challenging to treat as cytotoxic medications that cross the blood-brain barrier (BBB) are limited. In humans, intrathecal chemotherapy has an important role in hematopoietic CNS neoplasia, particularly in treating children or older patients to minimize exposure to radiotherapy. The extended biochemistry panel and electrolytes did not show any significant or specific changes except for elevated C-reactive protein (77 mg/L) (ref: and amp;lt; 10). After being pre-medicated with chlorphenamine (0.4 mg/kg IV), L-asparaginase was administered. During hospitalization, the patient also . . .

     

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