Investigating gene-environment interaction on attention in a double-hit model for autism spectrum disorder

HIGHLIGHTS

  • What: This study aimed to characterize a double-hit gene-environment rodent model for ASD, particularly focusing on the process of attention. This study explored the separate and combined effects of Cntnap2 deficiency and poly I:C maternal immune activation on relevant measures of attentional processing. This investigation showed that both MIA and genetic knockout can affect the cognitive process of attention separately;
  • Who: Melvin Maroon and collaborators from the Neuroscience Graduate Program, The University of Western Ontario, London, ON, Canada, Anatomy and have published the research work: Investigating gene-environment interaction on attention in . . .

     

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