HIGHLIGHTS
- What: At the same time, this study evaluated the probability of exceeding the upper limit (maximum concentration, 500 ng/ml) of the therapeutic window, which was the safety index. The study focused on the initial dose recommendation; thus, the course of long-term treatment needs to be adjusted based on TDM to evaluate the efficacy and safety of quetiapine.
- Who: Barbara Carpita et al. from the University of Pisa, Italy have published the Article: Model-informed precision dosing of quetiapine in bipolar affective disorder patients: initial dose recommendation, in the Journal: (JOURNAL)
- How . . .
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