Molecular basis of inhibitory mechanism of naltrexone and its metabolites through structural and energetic analyses

HIGHLIGHTS

• who: Martiniano Bello from the Laboratorio Diseño Desarrollo Nuevos Fármacos e Innovación Biotecnológica, Escuela Superior have published the research work: Molecular Basis of Inhibitory Mechanism of Naltrexone and Its Metabolites through Structural and Energetic Analyses, in the Journal: Molecules 2022, 4919 of /2022/
• what: The authors explore the structural and energetic basis of the mMOR in complex with naltrexone and its derivatives.
• how: The authors employed the high-resolution mMOR structure that has a high sequence identity (97%) with hMOR along with its active state to construct the hMOR . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.