Molecular sociology of virus-induced cellular condensates supporting reovirus assembly and replication

HIGHLIGHTS

• What: Unlike the core observed in this study with an open turret, the crystal_structure of the MRV core31, which was obtained on samples generated from chymotrypsin-digested virions, shows the turret in the same closed conformation as that in the virion (Fig S6). This study shows the power of integrating advanced techniques such as cryoET and cryoEM to study the MRV-induced cellular condensates at different time points, providing a "molecular sociology" perspective on the progression of MRV infection within cells. This study showcases the internal architecture of virus-induced cellular condensates, which have relatively long lifetimes . . .
  

   

  

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